I take it from the description that you are looking for insulation for a RepRap hot end. PEEK works well for load bearing components, and lasts well at 250 deg C. You can buy PEEK bar from RS, but it is expensive; the trick is to use as small a piece as possible. PTFE is normally used as a low friction liner inside the Hot end, it is fine at 250 deg C, but as others have noted it is very hazardous if you heat it to decomposition point, it generates Hydrogen Fluoride. I have found that PTFE is next to useless when used for load bearing, it quickly deforms. It is ok in compression, such as between two metal plates. Machinable ceramics would be ok, but they make PEEK look cheap!
If you want to avoid using PEEK take a look at some of the more modern hot end designs. The newest Makerbot hot end and the Huxley hot end (see the RepRap wiki) both use a short length of stainless steel tube as a thermal barrier, one end in the heater block, the other into a heatsink.
The design of the hot end seems to makes a huge difference to the performance of the Reprap. I would suggest you have a look at a number of the published designs on the RepRap wiki and
www.thingiverse.com.
Chris
Chris